Publications

Wen Ma, Shengjun You, Michael Regnier, J Andrew McCammon (2023). Integrating comparative modeling and accelerated simulations reveals conformational and energetic basis of actomyosin force generation. Proceedings of the National Academy of Sciences.

Skylar ML Bodt, Jinghua Ge, Wen Ma, David v Rasicci, Rohini Desetty, J Andrew McCammon, Christopher M Yengo (2023). Dilated cardiomyopathy mutation in beta-cardiac myosin enhances actin activation of the power stroke and phosphate release. bioRxiv.

Eliza Störmer, Jui-Hung Weng, Jian Wu, Daniela Bertinetti, Pallavi Kaila Sharma, Wen Ma, Friedrich W Herberg, Susan S Taylor (2023). Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW. Biochemical Journal.

Jui-Hung Weng*, Wen Ma*¶, Jian Wu, Pallavi Kaila Sharma, Steve Silletti, J Andrew McCammon, Susan Taylor (2023). Capturing differences in the regulation of LRRK2 dynamics and conformational states by small molecule kinase inhibitors. ACS chemical biology.

Momčilo Gavrilov, Joshua YC Yang, Roger S Zou, Wen Ma, Chun-Ying Lee, Sonisilpa Mohapatra, Jimin Kang, Ting-Wei Liao, Sua Myong, Taekjip Ha (2022). Engineered helicase replaces thermocycler in DNA amplification while retaining desired PCR characteristics. Nature communications.

Hamidreza Rahmani, Wen Ma, Zhongjun Hu, Nadia Daneshparvar, Dianne W Taylor, J Andrew McCammon, Thomas C Irving, Robert J Edwards, Kenneth a Taylor (2021). The myosin II coiled-coil domain atomic structure in its native environment. Proceedings of the National Academy of Sciences.

Sean P Carney, Wen Ma, Kevin D Whitley, Haifeng Jia, Timothy M Lohman, Zaida Luthey-Schulten, Yann R Chemla (2021). Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase. Nature communications.

Ruben D Elias, Wen Ma, Rodolfo Ghirlando, Charles D Schwieters, Vijay S Reddy, Lalit Deshmukh (2020). Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids. Proceedings of the National Academy of Sciences.

Qiang Zhang, Antonino Schepis, Hai Huang, Junjiao Yang, Wen Ma, Joaquim Torra, Shao-Qing Zhang, Lina Yang, Haifan Wu, Santi Nonell, Others (2019). Designing a green fluorogenic protease reporter by flipping a beta strand of GFP for imaging apoptosis in animals. Journal of the American Chemical Society.

Michael R Lawson, Wen Ma, Michael J Bellecourt, Irina Artsimovitch, Andreas Martin, Robert Landick, Klaus Schulten, James M Berger (2018). Mechanism for the regulated control of bacterial transcription termination by a universal adaptor protein. Molecular cell.

Wen Ma, Kevin D Whitley, Yann R Chemla, Zaida Luthey-Schulten, Klaus Schulten (2018). Free-energy simulations reveal molecular mechanism for functional switch of a DNA helicase. Elife.

Hang Yu, Wei Han, Wen Ma, Klaus Schulten (2015). Transient $β$-hairpin formation in $α$-synuclein monomer revealed by coarse-grained molecular dynamics simulation. The Journal of chemical physics.

Wen Ma, Klaus Schulten (2015). Mechanism of substrate translocation by a ring-shaped ATPase motor at millisecond resolution. Journal of the American Chemical Society.

Liuxuan Cao, Wei Guo, Wen Ma, Lin Wang, Fan Xia, Shutao Wang, Yugang Wang, Lei Jiang, Daoben Zhu (2011). Towards understanding the nanofluidic reverse electrodialysis system: well matched charge selectivity and ionic composition. Energy Environ. Sci..

David E Tanner, Wen Ma, Zhongzhou Chen, Klaus Schulten (2011). Theoretical and computational investigation of flagellin translocation and bacterial flagellum growth. Biophysical Journal.

Xueqing Zou, Wen Ma, Ilia a Solov'yov, Christophe Chipot, Klaus Schulten (2011). Recognition of methylated DNA through methyl-CpG binding domain proteins. Nucleic Acids Research.

Wei Guo, Liuxuan Cao, Junchao Xia, Fu-Qiang Nie, Wen Ma, Jianming Xue, Yanlin Song, Daoben Zhu, Yugang Wang, Lei Jiang (2010). Energy harvesting with single-ion-selective nanopores: a concentration-gradient-driven nanofluidic power source. Advanced functional materials.